Searchable abstracts of presentations at key conferences in endocrinology

ea0022p327 | Diabetes | ECE2010

Chitotriosidase activity predicts endothelial dysfunction in type 2 diabetes mellitus

Haymana Cem , Sonmez Alper , Tapan Serkan , Safer Umut , Celebi Gurkan , Ozturk Ozlem , Genc Halil , Dogru Teoman , Tasci Ilker , Erdem Gokhan , Taslipinar Abdullah , Aydogdu Aydogan , Yilmaz Mahmut I , Kurt Ismail , Kutlu Mustafa

The enzyme chitotriosidase (ChT) is secreted by activated macrophages and play active role in human immune response. ChT activity is increased in atherosclerosis in association to the extent of the disease. We investigated the relevance of ChT to endothelial functions and insulin resistance in patients with T2DM.Forty newly diagnosed and untreated patients with T2DM (male 17; age: 47.0±6.2 years) and 50 healthy volunteers (male 21; age: 50.2±8....